The Optics of Optical Coherence Tomography

Adaptive Optics for Optical Coherence Tomography

Clinical Applications of Optical Coherence Tomography in Ophthalmology

Assessment of the peripapillary nerve fiber layer and macular thickness can be determined in ophthalmology using optical coherence tomography (OCT). Decreased nerve fiber layer thickness and macular ganglion cell thickness in optic nerve ischemia have been correlated with visual field loss. OCT allows deep optic nerve head evaluation which helps understand pathophysiology of diseases.  Furtherm...

Experimental Visualization of Labyrinthine Structure with Optical Coherence Tomography

Introduction:Visualization of inner ear structures is a valuable strategy for researchers and clinicians working on hearing pathologies. Optical coherence tomography (OCT) is a high-resolution imaging technology which may be used for the visualization of tissues. In this experimental study we aimed to evaluate inner ear anatomy in well-prepared human labyrinthine bones.Materials and Methods:Thr...

Adaptive Optics Optical Coherence Tomography for in Vivo Retinal Imaging

Optical coherence tomography (OCT) is a non-invasive micrometer-resolution volumetric imaging modality that has been employed in diverse applications. In this thesis, we first describe a GPU accelerated program to perform FDOCT data processing and real time 3D volumetric rendering. The real time visualization of volumetric images provided by the GPU acceleration was essential to the rest of the...

Towards model-based adaptive optics optical coherence tomography.

The transfer function for optical wavefront aberrations in single-mode fiber based optical coherence tomography is determined. The loss in measured OCT signal due to optical wavefront aberrations is quantified using Fresnel propagation and the calculation of overlap integrals. A distinction is made between a model for a mirror and a scattering medium model. The model predictions are validated w...